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The Covid-19 jab made by German biopharmaceutical firm CureVac has shown full protection against the South African coronavirus variant and the original form of the virus, according to the results of a preprint study on mice.

Covid-infected mice that were vaccinated demonstrated "robust antibody responses" and developed complete protection against the virus, with a 100% survival rate, researchers said.

The animals were deliberately exposed to the B.1.351 strain of Covid – known as the South African variant – as well as the original form of the virus as part of a preclinical challenge infection study.

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German researchers gave the mice two doses of the mRNA-based CureVac jab 28 days apart and found that it "efficiently" blocked and reduced the replication of the virus in the animals.

The study, published in preprint format, used ACE2-transgenic mice, which are common in Covid-19 vaccine research as they exhibit similar responses to humans when infected with the virus.

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CureVac's chief scientific officer, Igor Splawski, said that the risk of more infectious coronavirus variants like B.1.351 pose a major threat to global immunization efforts.

"To our knowledge, this is the first challenge study in a human ACE2 transgenic mouse model of severe disease that shows complete protection against one of the most threatening virus variants," he said.

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from RT World News https://ift.tt/3ceLXTA

The Covid-19 jab made by German biopharmaceutical firm CureVac has shown full protection against the South African coronavirus variant and the original form of the virus, according to the results of a preprint study on mice.

Covid-infected mice that were vaccinated demonstrated "robust antibody responses" and developed complete protection against the virus, with a 100% survival rate, researchers said.

The animals were deliberately exposed to the B.1.351 strain of Covid – known as the South African variant – as well as the original form of the virus as part of a preclinical challenge infection study.

Also on rt.com
CureVac Covid-19 vaccine
Early data shows Curevac Covid-19 jab backed by Britain and Brussels is effective against UK and South Africa variants, CEO says

German researchers gave the mice two doses of the mRNA-based CureVac jab 28 days apart and found that it "efficiently" blocked and reduced the replication of the virus in the animals.

The study, published in preprint format, used ACE2-transgenic mice, which are common in Covid-19 vaccine research as they exhibit similar responses to humans when infected with the virus.

Also on rt.com
A police officer checks a commuter arriving from Poland, at the German-Polish border crossing in Frankfurt, Germany, March 22, 2021.
Germany to impose its harshest Covid-19 lockdown yet for Easter holiday as Merkel asks churches to hold online services only

CureVac's chief scientific officer, Igor Splawski, said that the risk of more infectious coronavirus variants like B.1.351 pose a major threat to global immunization efforts.

"To our knowledge, this is the first challenge study in a human ACE2 transgenic mouse model of severe disease that shows complete protection against one of the most threatening virus variants," he said.

Like this story? Share it with a friend!

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